1st February 2026

Categories: Information and Support

Promising results from early stage trial

An early stage American study published in The Lancet Oncology found that combining the oral drugs cabozantinib and temozolomide can slow the progression of advanced leiomyosarcoma (uterine and non-uterine).

In a clinical trial, 74% of patients with hard-to-treat, advanced sarcomas saw their disease stabilize for at least 12 weeks with manageable side effects. This lead in Phase 2 trial, would need to be followed up with successful larger trials before this combination became available to non-trial patients.

Read the full story at Northwestern Medicine.